Language

CAS No. 72509-76-3 | Felodipine

Name: Felodipine CAS No. 72509-76-3 MF:C18H19Cl2NO4 MW:384.25 Purity:98% Package: 5g,25g,200g,500g,1kg Worldwide Delivery

Categories：

Other Life Science Chemicals

Email：sale06@alfachem.cn

Inquiry

Chat Now

Product introduction

Introduction and application of CAS No. 72509-76-3 | Felodipine

Synonyms:ethylmethyl4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedica;

4-(2，3-Dichlorophenyl)-2，6-dimethyl-1，4-dihydro-3，5-pyridinedicarboxylicacidmethylethylester;

4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-5-methoxycarbonyl-3-pyridinecarboxylicacidethylester;

Specification:

ITEMS	SPECIFICATION
CAS	72509-76-3
MF	C18H19Cl2NO4
MW	384.25
Melting point	142-145°C
Boiling point	471.5±45.0 °C
Density	1.3506
Acidity coefficient	2.73±0.70
Color	Light yellow
Solubility	Solubility in DMSO is 28 mg/ml
Form	Solid
Storage condition	2-8°C

The mechanism of action of felodipine mainly involves two aspects:

①Can reduce systemic blood pressure;

② It can cause long-lasting dilation of glomerular afferent arterioles. Therefore, felodipine can increase renal blood flow and glomerular filtration rate, improve renal ischemia, and prevent disorders of renal blood vessels and glomerular structure and function. In addition, the glomerular basement membrane regulates the passage of macromolecular substances, which reduces the metabolic activity of the residual renal tissue to a certain extent and reduces the formation of free radicals to protect the kidneys. However, the shortcomings of felodipine have been determined Patients with kidney disease and massive proteinuria have significantly delayed kidney disease. The main function of felodipine is to reduce the patient's systolic blood pressure and pulse pressure, improve the endothelial function of blood vessels, and achieve anti-atherosclerosis.

Package and transportation :

Package: 5g,25g,200g,500g,1kg